I.S.S. is a 2023 American science fiction thriller film directed by Gabriela Cowperthwaite and written by Nick Shafir. The film stars Ariana DeBose, Chris Messina, John Gallagher Jr., Masha Mashkova, Costa Ronin, and Pilou Asbæk. The film follows two groups aboard the International Space Station—one of American astronauts and the other of Russian cosmonauts—who fight each other for the control of the station after a war starts between their countries.