Resident Evil: Afterlife is a 2010 action horror film written and directed by Paul W. S. Anderson. It is the second film in the series that he directed, after the first film. A direct sequel to Resident Evil: Extinction (2007), it is the fourth installment in the Resident Evil film series, which is loosely based on the video game series of the same name, and the first to be shot in 3D. It stars Milla Jovovich, Ali Larter, Kim Coates, Shawn Roberts, Spencer Locke, Boris Kodjoe, and Wentworth Miller.