Scream is a 1996 American slasher film directed by Wes Craven and written by Kevin Williamson. It stars David Arquette, Neve Campbell, Courteney Cox, Matthew Lillard, Rose McGowan, Skeet Ulrich, and Drew Barrymore. Set in the fictional town of Woodsboro, California, Scream's plot follows high school student Sidney Prescott (Campbell) and her friends, who, on the anniversary of her mother's murder, become the targets of a costumed serial killer known as Ghostface.