The Serpent Queen is an American historical drama television series about the life of Catherine de' Medici, the 16th century Queen of France, as portrayed by actress Samantha Morton. The series was created by Justin Haythe and is based on the 2004 nonfiction book Catherine de Medici: Renaissance Queen of France by Leonie Frieda. The Serpent Queen premiered on Starz on September 11, 2022. In October 2022, Starz renewed the series for a second season, which premiered on July 12, 2024. In October 2024, the series was canceled after two seasons.